Xadago
GENERIC NAME(S): Safinamide
Uses
Safinamide, sold under the trade name Xadago among others. Xadago is used with another drug (levodopa/carbidopa) to treat symptoms of Parkinson’s disease. It can help improve symptoms such as closeness, hardness and difficulty moving. It can also help reduce the amount of “off” time (slow speed or duration of immobility).
Xadago belongs to a class of drugs known as MAO inhibitors. It works by increasing the level of some natural substances (such as dopamine) in the brain. It is believed that Parkinson’s disease is due to very low dopamine in the brain.
How To Use Xadago
If you start taking Xadago or Safinamide from your pharmacist and you get a refill every time, then please read the Patient Information Letter. If you have any questions, ask your doctor or pharmacist.
Directly medicate this medicine with your mouth or without food, usually daily once.
Dosage is based on your medical condition and treatment response. Do not increase your dose or take it more than it has been fixed. There will be no improvement in your situation, and the risk of your side effects will increase.
Use this drug regularly to get the most benefit. To help you remember, take it at the same time every day.
Do not stop taking this medicine without consultation with your doctor. When this medicine suddenly stops, some conditions may get worse. Your dose may need to be gradually decreased.
The reaction of very serious hypertension can rarely occur if you eat Xadago and eat tyramine in large quantities for 2 weeks after it is stopped. Avoid foods that are high in tyramine, such as old things (such as Stilton cheese). Consult with your doctor or dietician what foods you should avoid and if you do not feel good after eating or drinking some foods while taking this medicine. See also the Side Effects section.
Tell your doctor if this medicine stops working well or if your condition worsens.
Side Effects
Dizziness or drowsiness may occur. If any of these effects remains or gets worse, then tell your doctor or pharmacist immediately.
To reduce the risk of dizziness and lighthouse, slowly rise while sitting or lying down, especially when you start taking Xadago or Safinamide for the first time.
Remember that your doctor has prescribed this drug because he or she has decided that the benefit is higher than the risk of side effects. Many people using this drug do not have serious side effects.
Tell your doctor immediately if you have a serious side effect, including: unconsciousness, loss of balance, changes in mental / mood (such as anxiety, movement, hallucinations), deterioration of deteriorating muscles / twitch / uncontrollable movements, abnormal strong insistence (e.g. ) Increase in gambling, sexual urges increased).
Some people taking Xadago have suddenly slept during their usual daily activities (such as talking on the phone, driving). In some cases, sleep has already happened without feelings of sleepiness. This sleep effect may occur at any time during treatment with Xadago, even if you have used this medicine for a long time. If you experience an increase in sleep during the day or fall asleep, do not drive or participate in other potentially dangerous activities, unless you have discussed this effect with your doctor. Your risk of the effect of this sleep increases with the use of alcohol or other medicines that can make you dull. See also the Precautions section.
This drug can increase serotonin and rarely cause a very serious condition, which is called serotonin syndrome / toxicity. The risk increases if you are taking other medicines which increase the serotonin, so tell your doctor or pharmacist about all the medicines that you take. Get medical help immediately when some of the following symptoms develop: Fast heartbeats, hallucinations, loss of coordination, severe dizziness, severe nausea / vomiting / diarrhea, muscle shaking, unexplained fever, abnormal movement or restlessness
Xadago can rarely cause the attack of hypertension (high blood pressure), which can be fatal. Many drug and food interactions can increase this risk (see how to use and drug interaction section). If any of these have serious side effects, seek medical help immediately: severe headache, fast / slow / irregular / fast heartbeat, chest pain, neck / cramps, severe nausea / vomiting, sweating / smelly skin (sometimes- Occasionally due to fever), broad pupils, vision changes (such as double / blurred vision), sudden sensitivity towards light (photophobia)
A very serious allergic reaction to this drug is rare. However, if you see symptoms of a serious allergic reaction, get medical help immediately, including: granular, itching / swelling (especially the face / tongue / throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you do not list other effects above, contact your doctor or pharmacist.
In America – Call your doctor for medical advice about side effects. You can notify the FDA of side effects on 1-800-FDA-1088 or www.fda.gov/medwatch.
In Canada – Call your doctor for medical advice about side effects. You can report the health effects of Canada on 1-866-234-2345.
Precautions
Before taking Xadago or Safinamide, tell your doctor or pharmacist whether you are allergic to it; Or if you have any other allergens. This product can have passive elements, which can cause allergic or other problems. Talk to your pharmacist for more details.
Before using this drug, tell your doctor or pharmacist your medical history, especially: liver disease, high blood pressure, mental / mood disorders (such as schizophrenia, bipolar disorder, depression), eye problems (such as macular degeneration, uveitis), sleep disorders.
Xadago can make you passable or dizzy. Alcohol or marijuana (cannabis) can make you more damp or dizzy. Unless you can safely do it, do not drive, use machinery, or do anything that requires caution. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis). See also the Side Effects section.
Before surgery, tell your doctor or dentist about all the products that you use (including prescription drugs, nonprescription drugs and herbal products).
During pregnancy, Xadago should be used only when it is clearly necessary. Discuss the risks and benefits with your doctor.
It is unknown if this medicine passes in breast milk. Consult your doctor before breastfeeding.
Over Dose
If someone is treated and has serious symptoms like having trouble going out or breathing, call 911. Otherwise, call the Poison Control Center immediately. US residents can call their local venom control center at 1-800-222-1222. Canadians can call a provincial poison control center.
Notes
Do not share this medication with others.
Labs and / or medical tests (such as blood pressure, liver function) should be done when you are taking this medication. Keep all medical and lab appointments.
People with Parkinson’s disease can increase the risk of developing skin cancer (melanoma). Tell your doctor immediately if you have a mole that grows or looks different, or if you have any other unusual skin changes. Ask your doctor if your skin should be checked regularly.
Missed Dose
If you miss a dose, then leave the missed dose. Take your next dose at regular times. Do not double the dose to catch up.
Storage
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Until instructed not to do so, do not flush the medicines in the toilet and do not drain in the drain. When this period expires or does not need it, then properly release this product. Consult your pharmacist or local waste disposal company.
Disclaimer: DrLinex has made every effort to ensure that all information is factually accurate, comprehensive and up-to-date. However, this article should not be used as a licensed health care professional’s choice of knowledge and expertise. You should always consult your doctor or other health care professional before taking any medication. The information given here is subject to change and it has not been used to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions or adverse effects. The lack of warning or other information for any drug does not indicate that the combination of medicine or medication is safe, effective or appropriate for all patients or all specific uses.
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