Tamiflu ( Oseltamivir)
Dosing & Uses
Dosage forms and powers
Capsule
• 30mg
• 45mg
• 75mg
• 30mg
• 45mg
• 75mg
Powder for oral suspension
• 6mg / ml
• 6mg / ml
Influenza A and B Prophylaxis
• 75 mg PO qday for at least 10 days
Dosage ideas
• Start within 48 hours of Exposure
• For community outbreaks, you can administer for 6 weeks
• Start within 48 hours of Exposure
• For community outbreaks, you can administer for 6 weeks
Influenza A and B Treatment
• 75 mg PO q12hr x5 day
Dosage Ideas
• Begin the influenza symptom within 48 hours of starting
• Begin the influenza symptom within 48 hours of starting
H1N1 Influenza A (Swine Flu) Prophylaxis (Off-label)
75 mg PO qDay
Dosage Ideas
• Postexposure prophylaxis: Begin within 7 days of exposure and continue for at least 10 days
• Preexposure prophylaxis: Start during the potential exposure period and continue after 10 days of the last known exposure.
• Postexposure prophylaxis: Begin within 7 days of exposure and continue for at least 10 days
• Preexposure prophylaxis: Start during the potential exposure period and continue after 10 days of the last known exposure.
H1N1 Influenza A (Swine Flu) Treatment (off-label)
75 mg PO q12hr x5 day
Dosage Ideas
• Begin the influenza symptom within 48 hours of starting
• Begin the influenza symptom within 48 hours of starting
Dose modification
Renal impairment
Treatment
• CRCL> 60 mL / min: no dose adjustment is necessary
• CRCL> 30 to 60 mL / min: 30 mg PO bid
• CRCL> 10 to 30 mL / min: 30 mg po qday
• End-stage kidney disease (do not undergo dialysis): Not recommended (not studied)
Prophylaxis
• CRCL> 60 mL / min: no dose adjustment is necessary
• CRCL> 30 to 60 mL / min: 30 mg po qday
• CRCL> 10 to 30 mL / min: 30 mg PO every other day
• End-stage kidney disease (do not undergo dialysis): Not recommended (not studied)
• CRCL> 60 mL / min: no dose adjustment is necessary
• CRCL> 30 to 60 mL / min: 30 mg PO bid
• CRCL> 10 to 30 mL / min: 30 mg po qday
• End-stage kidney disease (do not undergo dialysis): Not recommended (not studied)
Prophylaxis
• CRCL> 60 mL / min: no dose adjustment is necessary
• CRCL> 30 to 60 mL / min: 30 mg po qday
• CRCL> 10 to 30 mL / min: 30 mg PO every other day
• End-stage kidney disease (do not undergo dialysis): Not recommended (not studied)
Interections
Clopidogrel
Clopidogril reduces Tamiflu ( Oseltamivir) levels by others (see note). Use caution / monitor. Remarks: Clopidogrel can reduce serum concentrations of active metabolite (S) of Tamiflu ( Oseltamivir). .
Influenza virus vaccine quadrivalent
The influenza virus vaccine by Tamiflu ( Oseltamivir) pharmacodynamic rivalry reduces the effect of quadrivalent. Use caution / monitor. Avoid the administration of live-influenza influenza vaccine intravenous, within 2 weeks or 48 hours after the administration of Tamiflu ( Oseltamivir), unless prescribed for medical signs. Read More
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